# Ukraine comes under renewed Russian attack - Show: Global News Podcast - Published: 2026-10-23 - Canonical: https://podc.club/en/episode/135067274_155f07386f8c.html - Audio: http://open.live.bbc.co.uk/mediaselector/6/redir/version/2.0/mediaset/audio-nondrm-download-rss-low/proto/http/vpid/p0pj1qgg.mp3 - Source: Edited from a machine transcript of the first 30 minutes of the episode. Not an official summary. Hours after signaling readiness to resume peace negotiations, Russia launched three waves of ballistic missiles at Kyiv, killing two people in the capital and at least nine across Ukraine. A critical vulnerability in PHP—the programming language underpinning much of the internet—was discovered by AI researchers but leaked before a patch could be released, sending scanning activity against unpatched sites soaring. In the UK, an innovative platform-style clinical trial for Alzheimer's disease has begun, aiming to evaluate multiple treatments simultaneously. ## What this episode answers ### Why did Russia launch a major attack on Ukraine so soon after signaling willingness to resume peace talks? Russia showed no real change in position, firing 21 ballistic missiles in three waves at Kyiv just hours after Putin met Trump's envoy Steve Witkoff in St Petersburg; Zelensky called it a "demonstrative attack" and said it proved genuine pressure, not words, is what matters. ### How was the PHP vulnerability discovered and leaked, and what disruption has it caused? The PHP Foundation had been aware of a theoretical code flaw since 2024 but left it unaddressed; OpenAI and cybersecurity firm Wiz used frontier AI models to prove it was exploitable, but a human error caused the details to leak before the patch was released, after which attackers used AI to analyse the exploit and scanning activity against unpatched sites surged. ### How does Ukraine view Russia's peace overtures and America's role as mediator? Ukrainians harbour deep scepticism about Russia's sincerity and about the United States' impartiality as a mediator, with questions over whether Ukraine will have a seat at the table, whether its voice will be heard, and whether any deal will be fair still unresolved, according to BBC correspondent Dan Johnson reporting from Kyiv. ### How are the US and Israel reportedly planning to strike Iran? According to the New York Times, a three-day large-scale operation targeting oil facilities, nuclear sites, and ballistic-missile capabilities is being considered, potentially timed after the US midterm elections on 3 November, with the aim of pressuring Iran's near-collapsed economy into negotiations—though many analysts doubt it will materialise. ### What makes the new UK Alzheimer's clinical trial ADSmart different from conventional trials? ADSmart is a platform-style trial that tests multiple drugs simultaneously and can immediately drop any candidate showing no promise and switch to another; though standard in cancer care for roughly 20 years, this is the first application of the approach to Alzheimer's disease. ## Article ## Russia Strikes Kyiv Hours After Peace Signal The night sky over Kyiv was lit up on Wednesday (22nd) by a ferocious bombardment. President Zelensky reported that 21 ballistic missiles struck the capital in three waves, killing two people and wounding more than 30. Drone attacks elsewhere in the country killed a further seven. A Ukrainian Navy vessel was damaged at the southern port of Odessa, a bridge in the capital was destroyed—halting metro services and causing severe traffic congestion—and strikes on the power grid caused widespread outages. The assault came just hours after President Putin met Steve Witkoff, Donald Trump's special envoy, in St Petersburg, with Russia indicating it was in principle prepared to resume peace negotiations. Zelensky called the attack "demonstrative" and insisted there had been "no real change in Russia's position." He also pointedly quoted Witkoff's description of Putin as a "humanitarian," sardonically labelling the incoming missiles "rockets from Russia's humanitarian." Ukraine launched hundreds of drones toward Moscow in response; most were shot down, but there were injuries. BBC correspondent Dan Johnson, reporting from Kyiv, said Ukrainians harbour deep scepticism about both Russia's seriousness on peace and the United States' impartiality as a mediator. Questions about whether Ukraine will have a seat at the negotiating table, whether its voice will be heard, and whether any agreement will be fair remain unresolved. ## Critical PHP Vulnerability Found by AI, Leaked Before Patch A serious security flaw has been discovered in PHP, the programming language that underpins much of the internet. The PHP Foundation, the non-profit that manages PHP, had identified a theoretically problematic code defect in 2024 but set it aside because it could not confirm whether a human could actually exploit it. OpenAI and cybersecurity firm Wiz then used frontier AI models to analyse PHP and demonstrated that a specific, complex sequence of steps could allow an attacker to break into websites. The discovery should have been a clear example of AI used for good. Instead, a human error caused the vulnerability details to leak on Tuesday before the patch was released. Attackers, also using AI, began analysing the exploit, and scanning activity against unpatched sites surged dramatically. BBC cyber correspondent Joe Tidy cautioned that many of the "millions of attempts" are automated scans rather than genuine intrusions, and that scans do not necessarily lead to breaches. Even so, he warned that a breach will likely occur eventually: the vulnerability is complex, and AI is compressing what had previously been a protective window of time between discovery and exploitation. ## US and Israel Said to Be Weighing Strikes on Iran The New York Times has reported that the United States and Israel are drawing up plans to strike specific targets inside Iran. A large-scale, three-day operation targeting oil facilities, nuclear sites, and ballistic-missile capabilities is reportedly under consideration, with a possible timeline after the US midterm elections on 3 November. US officials reportedly believe such strikes could further cripple Iran's already near-collapsed economy and bring Tehran to the negotiating table. BBC Middle East analyst Sebastian Usher noted, however, that many doubt this would actually come to pass. Israel is due to hold elections within days, and there is speculation that Prime Minister Netanyahu, who is facing a difficult contest, could deliberately trigger a major conflict beforehand. Meanwhile, Iran-backed Houthi forces in Yemen are escalating attacks on Saudi Arabia daily; a strike on the international airport in the eastern city of Dammam killed two people—one Saudi and one Indian. The United States has been evacuating non-essential personnel from embassies across the region, a move widely read as a harbinger of broader conflict. ## UK Launches ADSmart Alzheimer's Trial A new Alzheimer's clinical trial called ADSmart has launched in the United Kingdom, designed to evaluate multiple treatments in parallel. Professor Paresh Malhotra of the UK Dementia Research Institute compared conventional single-drug trials to "building a stadium, playing one match, then knocking it down again," whereas ADSmart allows the stadium to host a full season. Any drug that shows insufficient promise can be dropped immediately and replaced with a different candidate. The platform-style approach has been standard in cancer treatment for roughly 20 years and was also used in the Covid RECOVERY trial. The first phase will test two drugs already approved for type-2 diabetes and ADHD. Circumstantial evidence and early-stage findings suggest these drugs could be beneficial in Alzheimer's, but no definitive trial had yet been conducted. Angela Bakshi, who received her diagnosis in January and is one of the first participants, said: "It might be a placebo, but it might help other people as well as me. Being able to take an active role is what matters." ## Takeaways - Russia launched three waves of ballistic missiles at Kyiv just hours after signaling readiness for peace talks, killing at least nine people across Ukraine and deepening Ukrainian scepticism about any genuine shift in Moscow's position. - A critical PHP vulnerability identified by AI leaked before a patch was released, with attackers also turning to AI to exploit it—a single incident that exposed both the promise and the danger of AI in cybersecurity. - The UK's new ADSmart Alzheimer's trial adopts a platform design to test multiple drugs simultaneously, bringing to Alzheimer's research an approach that has been standard in cancer care for roughly 20 years and could dramatically accelerate the search for treatments.